What is the easiest way to get to West 65TH Street from Grand Central Station?

West 65th St is accessible by subway:

Quickest way; Walk over to 42nd St-Bryant Park at 6th Av and take uptown (B)(D) train to 59th St-Columbus Circle, take Central Park West/60th St exit and walk north to 65th St.

Option 2

Uptown M5/M7 bus from 6th Av/42nd St stops at Broadway/66th St.

Option 3:

Take 34th St-bound (7) train to Shuttle train to Times Sq for uptown (1) to 66th St-Lincoln Center; (A)(C to 59th St-Columbus Circle.

Take the Times Square Shuttle (S) and transfer to the uptown 1 train to 66 Street - Lincoln Center station.

I'd take the 7 train to Times Sq. and change to the uptown 1 train.

I like Joseph's answer. The shuttle is more convenient than the 7 which is way down deep at GCT.

It's less than two miles, not a bad walk even rolling a suitcase.

Here's a map: https://www.google.com/maps/dir/Grand+central+stat...

Walk.  It's not that far.  Head north and count the streets.  GCT is on 42nd.