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Mrs. W!!!
Lv 5
Mrs. W!!! asked in Science & MathematicsMedicine · 1 decade ago

What does "use-dependent inhibition" mean as it relates to local anesthetics?

I'm studying for pharmacology and I don't quite follow the principle. Thanks for any assistance!

4 Answers

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  • sevenletters4me
    Lv 6
    1 decade ago
    Favourite answer

    Some local anesthetics bind preferentially to open Na channels (rather than closed or inactivated). So, the inhibition occurs primarily when the channels are being "used" a lot - during times of repetitive stimulation.

    btw - best wishes on your upcoming marriage!

  • ?
    Lv 4
    5 years ago

    Define Anesthetics

    Source(s): https://shrinke.im/a8M7v
  • Anonymous
    6 years ago

    This Site Might Help You.

    RE:

    What does "use-dependent inhibition" mean as it relates to local anesthetics?

    I'm studying for pharmacology and I don't quite follow the principle. Thanks for any assistance!

    Source(s): dependent inhibition relates local anesthetics: https://tr.im/Of7Sb
  • Anonymous
    5 years ago

    For the best answers, search on this site https://shorturl.im/avmXr

    generally local anaesthetic last for 45min.to 6hrs so i don't think there is any need to worry .if after 6 hrs u don't feel comfortable speak to ur doctor.

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